Ennigerloh / Düsseldorf, May 2017 - Tablet coating is becoming increasingly popular as a carrier of active ingredients in the pharmaceutical industry. This is a logical result of the ever-improving production processes that have been developed by special machine builders such as L.B. Bohle for years. At Interpack 2017, a bestseller takes center stage with the Bohle Film Coater BFC. The BFC enables active ingredient coating with highest precision. An alternative drum makes the coater particularly flexible. Thus, especially small tablets can be coated as well.
The significance of coating technologies has continued to increase in recent years. Tablets are mainly coated to control the release of active ingredients, protect the active ingredient against light and moisture or cover the bitter flavor. Especially the so-called active ingredient coating – i.e. the processing of active ingredients for tablet coating – is becoming increasingly important. Both versions can also be used in one product: Modern formulations often comprise several methods of active ingredient coating. This leads to long process times and an increased demand in machines which handle the complex tasks as automatically as possible. In this area, L.B. Bohle Maschinen + Verfahren GmbH, based in Ennigerloh (Westphalia), has established itself as a market leader with its film coaters.
Coating uniformity is a crucial factor for the production of coated tablets. This means that all tablets must be coated in exactly the same way. Bohle coaters like the BFC and the BTC achieve a standard deviation of less than two percent. This is unmatched in the market. BFC as technology leader
The coaters owe their high reliability to their design: The flat tablet bed in a long drum geometry as well as continuous adjustment of the inclination angle ensure optimal movement of the cores. Thanks to the systematic forced guidance in the drum of the BFC, the product is in constant movement. This prevents the formation of twins, i.e. tablets that stick together and are unusable.
Furthermore, the inclination angle of the housing can be adjusted and cleaned with high pressure and is suitable for so-called high-containment applications thanks to inflatable seals on the inspection doors. Each nozzle is also equipped with a pump head which constantly measures the pressure so that blocked nozzles can be identified immediately. The Bohle Coaters of the latest generation can be operated via the visualized "InTouch” user interface, which offers extensive batch management functions and a wide range of functions for recipe creation.More flexibility by customer request
In 2009 a slotted coater drum was developed as part of a customer project. One customer needed a coater to be able to coat miniature pellets with a diameter of less than three millimeters – a requirement that cannot be met by a system with standard perforation. Miniature tablets have been a common dosage form for some years now. They are especially suited for use of multi-particle dosage forms as they can be individually and flexibly dosed. To this end, they can either be filled into capsules or sachets or applied with miniature tablet dispensers. However, the small cores must be sufficiently stable, which is why they are often coated. Besides functionality, swallowing as well as taste and odor are positively influenced by the film coverings.
But the miniature tablets are often very fragile and may abrade or break due to strong fluidization required in the fluidized bed. Therefore, L.B. Bohle designed a slotted coater drum for moregentle handling of the small cores in 2009. This drum was designed with a corresponding perforation in which not only standard but also extremely small cores with a diameter of 1.5 millimeters can be coated. This gives the system maximum flexibility and enables processing of different particles.
Exhibitor Data Sheet