L.B. Bohle Maschinen + Verfahren GmbH

Postfach 11 62, 59303 Ennigerloh
Industriestr. 18, 59320 Ennigerloh
Germany

Telephone +49 2524 9323-0
Fax +49 2524 9323-399
info@lbbohle.de

Hall map

interpack 2017 hall map (Hall 17): stand B43

Fairground map

interpack 2017 fairground map: Hall 17

Contact

Tobias Borgers

Phone
+49 2524 - 93 23 0

Email
t.borgers@lbbohle.de

Our range of products

Product categories

  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.01  Complete lines for the production of pharmaceutical and cosmetic products

Complete lines for the production of pharmaceutical and cosmetic products

  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.02  Single machines /equipment for the production of pharmaceutical and cosmetic products
  • 06.02.03  Coating systems for pharmaceutical and cosmetic products
  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.02  Single machines /equipment for the production of pharmaceutical and cosmetic products
  • 06.02.10  Fluid bed systems for pharmaceutical and cosmetic products

Fluid bed systems for pharmaceutical and cosmetic products

  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.02  Single machines /equipment for the production of pharmaceutical and cosmetic products
  • 06.02.11  Granulating machines for pharmaceutical and cosmetic products
  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.02  Single machines /equipment for the production of pharmaceutical and cosmetic products
  • 06.02.19  Mixers for pharmaceutical and cosmetic products
  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.02  Single machines /equipment for the production of pharmaceutical and cosmetic products
  • 06.02.20  Pharma extruders for pharmaceutical and cosmetic products

Pharma extruders for pharmaceutical and cosmetic products

  • 06  Machines and equipment for the production of pharmaceuticals and cosmetics
  • 06.03  Operating and auxiliary equipment for the production of pharmaceuticals and cosmetics
  • 06.03.09  Laboratory equipment - pharmacy and cosmetics

Our products

Product category: Coating systems for pharmaceutical and cosmetic products

BFC - High-End Bohle Coater for pharmaceutical applications

The high-end version of the Bohle coater designed specifically for high speed, problem-free coating, providing unparalleled tablet uniformity and efficiences. A high containment execution is also available.

Benefits of the Bohle Film Coater:
  • state of the art coating technology
  • homogeneous mixing due to patented spirals
  • gentle mechanial treatment of tablets cores to avoid edging and breaking
  • simple and quick discharging by reversing the direction of rotation
  • nozzles with AB-caps ensure long enduring operation
  • geometrical similarities of all machine sizes ensure secure scale-up conditions
  • unique cleaning abilities with integrated high-pressure washing-system
  • high sophisticated control system

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Product category: Granulating machines for pharmaceutical and cosmetic products

Fluid bed system Bohle Uni Cone BUC ®

Using a tangential fluid bed system represents state of the art technology in pharmaceutical manufacturing for particle coating, granulation and drying.

With the innovative and patented Bohle Uni Cone BUC® process a complete fluidization is assured which leads to a high coating uniformities and high yields in the final product due to the absence if particle twinning. Bohle Uni Cone BUC® is the productive, practical and precise alternative to conventional Wurster processing.

The BFS features a broad range of extension options for Bottom Tangential Spray Granulation as well as Bottom Tangential Spray Coating. All production systems are 12 bar shock pressure resistant.

A minimum of six seperately cleanable filter elements in the granulating system ensure that air flow through the product bed is not interrupted. The Bohle Fluid Bed System BFS is designed for through-the-wall installation.

The filter dome is attached to a frame in the engineering area.

The pivoting design of the product container with integrated inlet plenum is attached to the frame permitting easy access to the floor beneath the system. Two inflatable seals ensure air-tight sealing of the system.

The tangential base eliminates the need to remove the product container from the system to discharge it. The product is set in rotation by the tangential slotted openings in the base. A valve in the product container wall above tie base allows the content to be discharged directly. The centrifugal forces occurring during the product rotation ensure complete discharge.

The slotted base of the fluid bed system ascends conically towards the center, resulting in high stability of the base and process-related advantages through enhanced blending of the product. 

The discharge valve can also be used for vacuum assisted discharge of the product. The filter bag of each filter cartridge can be exchanged separately and easily. Furthermore the complete filter unit can be lowered for access from the floor level.

Benefits:

  • inline sieving and product transfer
  • 12 bar pressure shock resistant - optimum conditions for containment applications, no effect on environment in case of accident
  • integration of PAT, NIR and WIP
  • fliter cleaning by patent / patented diffuser
  • electrical drop down filter movement
  • filter cartridges with spindle drive
  • vacuum changing
  • removable bottom plate

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Product category: Granulating machines for pharmaceutical and cosmetic products

VMA - Single pot granulator for pharmaceutical applications

The VMA single pot granulator is a granulating and drying system specifically optimized for pharmaceutical applications. The Vagumator® single pot systmes are designed for closed, dust-free processing of pharmaceutical granules from charging through dicharge including in-line milling.

Mixing, granulation and drying cycles are completed in a single machine under contained conditions.

The impeller, with its high shear and compression, ensures effective granulation. The chopper prevents excessive granule growth and distributes the granulating liquid within the product.

The Vagumator® VMA offers optimal conditions for wet granulation of high-quality pharmaceutical products.

Ease-of-use and easy cleaning were key factors in the machine design. Large surfaces make for the machine’s easy cleaning. The top drive ensures that the seals of the impeller and chopper shafts are not exposed to the product, allowing for a longer service life. The centrally-positioned base outlet guarantees controlled product discharge and complete water discharge after cleaning.

The flexible machine is state-of-the-art, and exceeds current GMP requirements with regard to design, handling and control.

Benefits:

  • small footprint
  • easy through-the-wall-assembly
  • gravity feeding is standard
  • installation in hazardous areas
  • switch cabinet on board

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Product category: Mixers for pharmaceutical and cosmetic products

Blending systems for pharmaceutical applications

Bohle is the world’s leading manufacturer of blenders. The high efficiency of the Bohle blending systems is based on the revolutionary and patented counter-current process principle.

The range of Bohle blending systems shows the flexibility of our engineering and manufacturing departments. Bohle blenders can be adjusted and used in any imaginable pharmaceutical production situation.

No matter what kind of container you use, round and square, Bohle blenders can handle them with
excellent blending results.

Bohle provides blenders featuring a variety of different load bearing capacities:

  • standard arm connection and clamps
  • round forks on the lift arm
  • lift arm with eccentric, power and hydraulic clamps

The high efficiency of the Bohle blending systems is based on the revolutionary and patented counter-current process principle. There are numerous benefits: Effective blending volume of 20-85% of the rated volume.
The Bohle blending systems allow homogeneous blending of dry powder batches with its patented blending
elements mounted to the inside of the container lid. The blending procedure can be scaled up from
4 – 12,000 liters.

For full flexibility the blending containers can be exchanged to use different volumes if required. Due to the patented Bohle blending systems each blending container can be used for effective mixing between 20 – 85 %
of the total container volume for densities between 0.2 – 1.2 kg/l.

The Pharma Blender is a stationary blending device, consisting of:

  • PM machine body with load suspension device
  • electrical switch cabinet integrated in machine body.A separate installation is optional upon request
  • separate operator panel
  • safety light barrier or laser scanner as an option
  • The blending operation is a fully contained and closed process. Each container has an inner lid for filling procedures.

An extended hoist allows the blender to be also used as a milling station for bin to bin transfer.

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Product category: Complete lines for the production of pharmaceutical and cosmetic products

Compact granulation system: Bohle Compact Unit - Small footprint, high quality

The individual components of the High Shear Granulator GMA, wet sieve BTS, Fluid Bed System BFS and Bohle Uni Cone BUC®, cyclone separator and dry sieve BTS are optimally integrated into the Compact Unit. This integration covers process, cleaning, control and explosion protection as well as qualification.

The Compact Unit is a compelling solution when traditional wet granulation must be realized economically and ergonomically. Featuring many technological advances and inherent safety considerations, the Compact Unit creates an industry benchmark.

Small footprint, flexible application and smooth production processes are decisive criteria for investment in the pharmaceutical granulation system. In this respect, L.B. Bohle sets standards with the Compact Unit.

Benefits of the Compact Unit:

  • GMA Granulator® and Bohle fluid bed system BFS built into the wall right next to each other
  • small footprint and minimized room height
  • multipurpose use for various processes
  • single operator  panel to serve both machines
  • single WIP-skid to serve both machines
  • 12 bar pressure shock resistant design

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Product category: Coating systems for pharmaceutical and cosmetic products

Bohle Tablet Coater BTC. The economical choice for all coating applications

L.B. Bohle has developed the future of tablet coating, the high-efficiency Bohle Tablet Coater (BTC). The tablet coater reduces processing times up to 35 percent compared to conventional tablet coating systems, yielding significant cost savings and improved campaign efficiency while maintaining cGMP standards.

The Bohle Tablet Coater BTC provides superior coating uniformity, producing considerably fewer rejects and using less coating material. L.B. Bohle’s patented air flow bed technology eliminates spray drying, thereby reducing waste while lengthening campaigns between cleaning. It also promotes uniform tablet coating with a high-quality, defect-free film coat.

The tablet coater’s elongated coating pan provides a larger tablet spraying surface accommodating up to 10 spray nozzles, which delivers more suspension solution and reduces overall coating time. The Bohle Tablet Coater BTC’s integrated mixing baffles are double-helix shaped to ensure thorough tablet mixing with gentle handling. The baffle design provides 100-percent tablet discharge, increasing campaign efficiency.

The Bohle Tablet Coater BTC is the most economical alternative for all common coating applications.

The benefits of the Bohle Tablet Coater BTC:

  • state of the art coating technology
  • homogeneous mixing due to patented spirals
  • gentle mechanical treatment of tablet cores to avoid edging and breaking
  • simple and quick discharging by reversing the direction of rotation
  • nozzles with AB-caps ensure long enduring operation
  • minimizing loss of spraying solution to to a value below 5 %
  • geometrical similarities of all machine sizes ensure secure scale-up conditions
  • friendly operator software and visualization

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Product category: Granulating machines for pharmaceutical and cosmetic products

Compactor BRC 25 and BRC 100 - Economical dry granulation

In the dry granulator powders are processed into fluid granules. The objective in the pharmaceutical industry is to process a granule with defined density or porosity for immediate tabeletting thereafter. The powder is fed via a dosing unit, compacted between two rollers with gaps ranging from 1 to 6 mm and discharged as scabs.

The impact on the rollers, as well as the gap width are monitored sensorially and integrated into a control circuit to ensure continuous optimum process parameters. The chopper unit below the compact rollers processes scabs into granules. The unit is equipped with a conical sieve with exchangeable sieve units for processing different particle sizes. Especially the control of the pressing force via standard hydraulic systems constitutes a great problem, when the process is aimed to comply with “hygienic design”. With the innovative electro-mechanical batch L.B. Bohle is able to solve this problem.

With the Bohle BRC dry granulator, frequent axis adjustment as with traditional roller compactors is a thing of the past. Thanks to a special bearing method, the axes are mechanically stable so that elastic deformation is prevented. This eliminates the need for complete axes control!

Moreover, the dry granulator BRC is low maintenance. Even when cleaning is required, only four screws must be removed. Furthermore, Bohle engineers reduced the overall height by 20 percent.

Bohle is now able to offer the customers machines and processes for all stages of the granulation process with the new BRC – continuously, and with the proven Bohle quality.


  • The advantages of the new Bohle - BRC dry granulator:

  • Minimal material loss due to precise control of the compression force with an innovative electromechanical roller drive
  • Constant ribbon properties assured with sensitive gap width control
  • Easy handling and short mounting procedures
  • Hygienic design and effective cleaning by integrated WIP nozzles
  • Versatile and gentle particle size adjustment with integrated Bohle Turbo Sieve (BTS 200)
  • PAT tool integration possible

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Product category: Granulating machines for pharmaceutical and cosmetic products

Bohle continuous granulator BCG

Advantages of the BCG:

  •  Pharma-compliant design
  •  Truly continuous process
  •  Flexible screw layout – adapting to customer process
  •  Independent torque measurements for both screws
  •  Integrated thermal control for screw housing
  •  Designed for blending and wet granulation

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Product category: Complete lines for the production of pharmaceutical and cosmetic products

Continuous processing unit

The continuous production line is a modular solution. In contrast to existing systems, the modular system allows the flexible arrangement of different unit operations, opening the path for a specialized solution depending on the requirements of the customer.

The continuous production line provides a nominal output range of approx. 5 to 25 kg/h. The production line is designed as a flexible layout concept, allowing exchanging or removing single unit operations. In this way the three most commonly production layouts direct compression, wet granulation and dry granulation can be realized

The inclusion of dry compaction in a continuous working process is unique and it is much more economic and less energy intensive in contrast to the wet granulation process. By the integrated analytics the interim storage and the laboratory analytics will mostly become obsolete. The costs for storage room and stored material will be extremely reduced. The manufacturing process will be also reduced, allowing higher production capacities and faster response to short-term demands. With the continuous processes the scale up of the production output is achieved by extending the production time, rather than by batch sizes.

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Product category: Coating systems for pharmaceutical and cosmetic products

ROB 50 optimizes production processes in continuous and batch-oriented processing

L.B. Bohle presented the ROB 50 as innovative solution to automate and optimize production processes in both continuous and batch-oriented production of solid dosage forms.
The ROB 50 is a robotic system for handling of tablet containers, to close the gap between the tablet press and film coating process.

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Product category: Coating systems for pharmaceutical and cosmetic products, Laboratory equipment - pharmacy and cosmetics

Bohle Film Coater BFC 5 - Laboratory Coater

The Bohle Film Coater BFC 5 is a stand-alone unit. The entire air technique as well as electrical and control technique is integrated in the system.

Multipanel visualization with touch panel, operator unit is attached to coater. An electrical connection and a compressed air connection are required for operation.

The pan can be dismantled, which results in easy cleaning. Furthermore, a larger pan can be optionally installed. The Coater BFC 5 can be operated with two pans, whereby the smaller pan can be separated with cutting disc.

The Bohle Film Coater BFC 5 is suitable for batch sizes of 2 to 13 liters. A transport trolley is supplied for easy discharge and for pan transport.

  • Benefits of the Bohle Film Coater BFC 5:

BFC 5 can be operated with one of two differtent pan sizes. Coater pans are changed manually
the capacity of the smaller pan can be reduced with a divider plate
batch sizes from 2 to 13 liters
computerized Win CC visualization with extensive batch management tools and broad range of tools for preparing recipes
multipanel visualization with touch panel, operator panel is attached to the coater
manual cleaning

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Product category: Coating systems for pharmaceutical and cosmetic products

Bohle Film Coater BFC TriPan - with three exchangeable pans

The BFC TriPan Film Coater is designed specifically for high speed, problem free coating, providing unparalleled tablet uniformity and efficiencies. TriPan is a Bohle Film Coater with a suspension supply  via a single pump head.

TriPan can be operated with three pans for batch sizes of 7 to 75 liters.
TriPan can be operated with three pans for batch sizes of 7 to 75 liters. Change of pans using a lifting device. Computer-supported InTouch visualization with extensive batch management tools and a broad range of tools for preparing recipes. Easy cleaning of the BFC TriPan thanks to high pressure cleaning of the pan inside.

Benefits of the Bohle Film Coater BFC TriPan:

  • batch sizes from 7 to 75 liters
  • computerized InTouch visualization with extensive batch management tools and a broad range of tools for preparing recipes
  • easy cleaning thanks to a high pressure system on the inside of the pan
  • suspension supply via a single punp head

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Product category: Mixers for pharmaceutical and cosmetic products, Laboratory equipment - pharmacy and cosmetics

LM 40 - Laboratory blender for pharmaceutical apllications

The Bohle Laboratory Blender LM 40 is a mobile unit. The blender itself is integrated into a frame with lock casters. A plexiglas cover protects the type MC blending containers (standard container sizes: 5, 10, 20 and 40 litres) during rotation to ensure full worker safety.
The Bohle blending technology has been demonstrated to be fully scalable from five liters (LM 40, as presented) up to 12,000 liter blenders.
The cover is opened to allow access to the MC blending container. If the cover is opened during blending, a safety switch will stop the unit. The blender has a drive unit with a bevel gear motor and a potentiometer control to infinitely adjust the rotational speed.
The Bohle blending system provides the maximum in blending performance, precision and accuracy. A laboratory scale blender is available for trials in our Service Center in Ennigerloh, Germany.

The advantages of the LM 40:
  •  mobile unit
  •  results fully scalable from 5 up to 12,000 liters
  •  integrated safety switch
  •  operator-friendly, modular and compact design
  •  easy, fast and complete discharge

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About us

Company data

Export content

> 75%

Number of employees

100-499

Foundation

1981

Target groups
  • Industrial goods
  • Pharmaceuticals
  • Consumer goods (non-food)

Company information as a PDF file